Table 3.
Inflammatory proteins included in multiplex panel B (cyto-plex).
| Gene Name / Protein Name | Uniprot Entry | Protein Names | Function | Reference |
|---|---|---|---|---|
| CCL2/MCP1 | P13500 | C-C motif chemokine 2, Monocyte chemotactic protein 1 | Angiogenesis, chemotaxis | [14], [37] |
| CCL3/MIP-1α | P10147 | C-C motif chemokine 3, Macrophage inflammatory protein 1-alpha | Monokine with inflammatory and chemokinetic properties | [73] |
| CCL5/RANTES | P13501 | C-C motif chemokine 5 | Chemoattractant | [44] |
| CNTF | P26441 | Ciliary neurotrophic factor | Axon regeneration | NA |
| CXCL10/IP-10 | P02778 | C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein | chemotaxis, differentiation, activation of peripheral immune cells, cell growth, apoptosis, modulation of angiostatic effects | [30] |
| CXCL11/I-TAC | O14625 | C-X-C motif chemokine 11, Interferon-inducible T-cell alpha chemoattractant | Chemotaxis, skin immune responses | NA |
| FGF-1 | P05230 | Fibroblast growth factor 1 | cell survival, cell division, angiogenesis, cell differentiation, cell migration | NA |
| CXCL1/GRO-α | P09341 | Growth-regulated alpha protein | Chemotaxis, inflammatory response | [26] |
| IL-12A | P29459 | Interleukin-12 subunit alpha | Cytokine, growth factor | [7] |
| IL-13 | P35225 | Interleukin-13 | Cytokine, inflammatory response | NA |
| IL-1α | P01583 | Interleukin-1 alpha | Inflammatory response, angiogenesis, cell division | [30] |
| IL-1β | P01584 | Interleukin-1 beta | Inflammatory response, angiogenesis, cell division, cell migration | [26], [30], [35] |
| IL-6 | P05231 | Interleukin-6 | Acute-phase response, immunity, tissue regeneration, metabolism | [7], [37] |
| CXCL8/IL-8 | P10145 | Interleukin-8 | Chemotaxis, angiogenesis, inflammatory response | [7], [26], [41], [44]] |
| MMP9 | P14780 | Matrix metalloproteinase-9 | Extracellular matrix organization, apoptosis, response to stress | [7] |
| NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform, heregulin | Cell growth, differentiation, wound healing | NA |
| RETN | Q9HD89 | Resistin | Hormone, fat cell differentiation | NA |
| TGF-β1 | P01137 | Transforming growth factor beta-1 proprotein | Cell growth, migration, differentiation, chemotaxis, inflammatory response, vasculogenesis | [33] |
| TIMP1 | P01033 | Metalloproteinase inhibitor 1, tissue inhibitor of metalloproteinases 1 | Extracellular matrix disassembly, cell differentiation, migration, cell death | [70] |
| TNF-α | P01375 | Tumor necrosis factor | Cell death, cell proliferation, angiogenesis, inflammatory response | [73] |