Table 3.
Stratified analysis for the correlation between TMAO and intermediate to high coronary atherosclerotic burden in CHD individuals
| Subgroups | N | OR (95% CI) | p for interaction |
|---|---|---|---|
| Sex, n (%) | 0.324 | ||
| Male | 201 | 1.02 (1.01, 1.07) | |
| Female | 227 | 1.05 (1.01, 1.13) | |
| Age, years | 0.267 | ||
| < 65 | 213 | 1.03 (1.01, 1.08) | |
| ≥ 65 | 215 | 1.08 (1.03, 1.15) | |
| BMI, kg/m 2 | 0.421 | ||
| < 25 | 176 | 1.02 (1.01, 1.05) | |
| ≥ 25 | 246 | 1.06 (1.03, 1.12) | |
| Current smoking | 0.101 | ||
| No | 227 | 0.95 (0.91, 1.06) | |
| Yes | 196 | 1.04 (1.01, 1.07) | |
| Current drinking | 0.382 | ||
| No | 292 | 1.05 (1.02, 1.09) | |
| Yes | 128 | 1.09 (1.05, 1.14) | |
| Hypertension | 0.807 | ||
| No | 116 | 1.06 (1.02, 1.19) | |
| Yes | 308 | 1.13 (1.05, 1.18) | |
| Self-reported diabetes | 0.196 | ||
| No | 221 | 1.04 (1.01,1.10) | |
| Yes | 204 | 0.99 (0.95, 1.02) | |
| Self-reported hyperlipidemia | 0.694 | ||
| No | 121 | 1.03 (1.01, 1.09) | |
| Yes | 298 | 1.07 (1.02, 1.16) | |
| Family history of CHD | 0.719 | ||
| No | 249 | 1.07 (1.03, 1.18) | |
| Yes | 154 | 1.09 (1.02, 1.23) | |
| LDL-C, mmol/L | 0.592 | ||
| < 1.8 | 134 | 1.07 (1.03, 1.18) | |
| ≥ 1.8 | 271 | 1.05 (1.03, 1.12) | |
| Hcy, µmol/L | 0.105 | ||
| < 15 | 215 | 1.03 (1.01, 1.06) | |
| ≥ 15 | 93 | 1.08 (1.02, 1.17) |
SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; CHD, coronary heart disease; LDL-C, low density lipoprotein cholesterol; TMAO, trimethylamine N-oxide; OR, odds ratio; Cl, confidence interval