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. 2024 May 21;23:159. doi: 10.1186/s12936-024-04979-y

Fig. 4.

Fig. 4

Correlation between pharmacokinetic parameters (CMAX and AUC24) and the median haemoglobin drop for primaquine (A, B), carboxy-primaquine (C, D), and primaquine cabarmoyl-glucuronide (E, F) in G6PD-deficient individuals (n = 18). Blue lines and shaded areas represent the linear regression with associated prediction intervals. Black circles and grey lines represent individual’s mean and range of observed haemoglobin drop. None of these correlations are significantly different from the zero-slope