Table 2.
Univariate analysis for the association of patient characteristics with 3-month poor functional outcome in patients who received reperfusion therapy
| Characteristics | Total (n = 124) | Left hemisphere | Right hemisphere | ||||
|---|---|---|---|---|---|---|---|
|
|
|
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| mRS 0–2 (n = 40) | mRS 3–6 (n = 27) | P-value | mRS 0–2 (n = 38) | mRS 3–6 (n = 19) | P-value | ||
| Age, years | 64 (56–71) | 62 (50–68) | 68 (59–74) | 0.052 | 66 (56–73) | 67 (57–74) | 0.939 |
| Male, n (%) | 88 (71.0) | 31 (77.5) | 20 (74.1) | 0.747 | 28 (73.7) | 9 (47.4) | 0.050 |
| Hypertension, n (%) | 74 (59.7) | 22 (55.0) | 17 (63.0) | 0.517 | 22 (57.9) | 13 (68.4) | 0.442 |
| Hyperglycemia, n (%) | 39 (31.5) | 11 (27.5) | 7 (25.9) | 0.887 | 13 (34.2) | 8 (42.1) | 0.560 |
| Hyperlipidemia, n (%) | 43 (34.7) | 19 (47.5) | 7 (25.9) | 0.075 | 14 (36.8) | 3 (15.8) | 0.101 |
| Coronary artery disease, n (%) | 15 (12.1) | 5 (12.5) | 3 (11.1) | 0.999 | 6 (15.8) | 1 (5.3) | 0.405 |
| Atrial fibrillation, n (%) | 11 (8.9) | 2 (5.0) | 1 (3.7) | 0.999 | 5 (13.2) | 3 (15.8) | 0.999 |
| Smoke, n (%) | 52 (41.9) | 18 (45.0) | 13 (48.1) | 0.800 | 17 (44.7) | 4 (21.1) | 0.081 |
| Statins, n (%) | 49 (39.5) | 15 (37.5) | 14 (51.9) | 0.245 | 12 (31.6) | 8 (42.1) | 0.432 |
| Aspirin, n (%) | 44 (35.5) | 14 (35.0) | 12 (44.4) | 0.436 | 11 (28.9) | 7 (36.8) | 0.546 |
| Clopidogrel, n (%) | 29 (23.4) | 8 (20.0) | 8 (29.6) | 0.365 | 9 (23.7) | 4 (21.1) | 0.999 |
| Baseline NIHSS | 11 (8–14) | 10 (7–12) | 14 (9–18) | 0.015 | 10 (7–11) | 12 (10–15) | 0.011 |
| Arterial steno-occlusion site, n (%) | 0.362 | 0.175 | |||||
| ICA | 24 (19.4) | 9 (22.5) | 3 (11.1) | 9 (23.7) | 3 (15.8) | ||
| MCA | 89 (71.8) | 29 (72.5) | 21 (77.8) | 27 (71.1) | 12 (63.2) | ||
| ICA/MCA tandem | 11 (8.9) | 2 (5.0) | 3 (11.1) | 2 (5.3) | 4 (21.1) | ||
| Treatment option | 0.879 | 0.115 | |||||
| IVT | 42 (33.9) | 14 (35.0) | 9 (33.3) | 10 (26.3) | 9 (47.4) | ||
| EVT | 70 (56.5) | 23 (57.5) | 15 (55.6) | 25 (65.8) | 7 (36.8) | ||
| Combined | 12 (9.7) | 3 (7.5) | 3 (11.1) | 3 (7.9) | 3 (15.8) | ||
| ASPECTS score | 6 (4–7) | 7 (5–8) | 5 (3–7) | 0.017 | 6 (5–8) | 4 (3–6) | 0.005 |
| Caudate nucleus, n (%) | 47 (37.9) | 12 (30.0) | 15 (55.6) | 0.036 | 13 (34.2) | 7 (36.8) | 0.844 |
| Lenticular nucleus, n (%) | 70 (56.5) | 18 (45.0) | 13 (48.1) | 0.800 | 27 (71.1) | 12 (63.2) | 0.546 |
| Internal capsule, n (%) | 41 (33.1) | 15 (37.5) | 10 (37.0) | 0.969 | 7 (18.4) | 9 (47.4) | 0.022 |
| Insula, n (%) | 64 (51.6) | 16 (40.0) | 18 (66.7) | 0.032 | 16 (42.1) | 14 (73.7) | 0.024 |
| M1, n (%) | 31 (25.0) | 5 (12.5) | 9 (33.3) | 0.040 | 10 (26.3) | 7 (36.8) | 0.413 |
| M2, n (%) | 54 (43.5) | 13 (32.5) | 16 (59.3) | 0.030 | 13 (34.2) | 12 (63.2) | 0.038 |
| M3, n (%) | 48 (38.7) | 16 (40.0) | 11 (40.7) | 0.952 | 10 (26.3) | 11 (57.9) | 0.020 |
| M4, n (%) | 48 (38.7) | 6 (15.0) | 13 (48.1) | 0.003 | 18 (47.4) | 11 (57.9) | 0.454 |
| M5, n (%) | 95 (76.6) | 28 (70.0) | 19 (70.4) | 0.974 | 31 (81.6) | 17 (89.5) | 0.441 |
| M6, n (%) | 59 (47.6) | 14 (35.0) | 17 (63.0) | 0.024 | 15 (39.5) | 13 (68.4) | 0.039 |
NIHSS: National Institute of Health Stroke Scale; mRS: modified Rankin Scale; ICA: internal carotid artery; MCA: middle cerebral artery; IVT: intravenous thrombolysis; EVT: endovascular thrombectomy; ASPECTS: Alberta Stroke Program Early CT Score. The bold fonts indicate statistical significance (P < 0.05).