Table 2.
Hematopoietic stem cell and immune cell subset normal values and characteristics based on sex in the bone marrow of healthy donors (absolute numbers and percentages).
| Parameters | group | Mean | SEM | Median | SD | Normal Values |
|---|---|---|---|---|---|---|
| HSC (abs) | All | 216.9 | 10.9 | 211.3 | 93.0 | 71–552 |
| Male | 220.2 | 16.3 | 221.9 | 90.7 | 81–430 | |
| Female | 214.5 | 14.8 | 202.3 | 95.7 | 71–552 | |
| HSC (%) | All | 0.30 | 0.01 | 0.30 | 0.08 | 0.10–0.50 |
| Male | 0.29 | 0.01 | 0.30 | 0.09 | 0.16–0.50 | |
| Female | 0.30 | 0.01 | 0.30 | 0.08 | 0.10–0.50 | |
| Lymphocyte (cells/μl) | All | 6130 | 381 | 5272 | 3169 | 1356–17109 |
| Male | 5822 | 493 | 5219 | 2789 | 1356–13533 | |
| Female | 6175 | 527 | 5170 | 3418 | 1968–17109 | |
| Lymphocyte (%) | All | 9.68 | 0.42 | 9.00 | 3.42 | 5.00–18.00 |
| Male | 9.21 | 0.50 | 9.00 | 2.63 | 6.00–15.00 | |
| Female | 10.00 | 0.62 | 9.00 | 3.87 | 5.00–18.00 | |
| T cells (cells/μl) | All | 3794 | 189 | 3486 | 1630 | 1006–8814 |
| Male | 3793 | 287 | 3465 | 1626 | 1006–8814 | |
| Female | 3795 | 255 | 3610 | 1653 | 1279–7817 | |
| T cells (%) | All | 64.63 | 1.13 | 65.5 | 9.22 | 39.00–85.00 |
| Male | 65.74 | 1.24 | 66.00 | 6.45 | 53.00–78.00 | |
| Female | 63.87 | 1.72 | 64.00 | 10.75 | 39.00–85.00 | |
| CD4+ T cells (cells/μl) | All | 1773 | 89 | 1613 | 767 | 460–3768 |
| Male | 1702 | 123 | 1563 | 696 | 460–3442 | |
| Female | 1827 | 126 | 1696 | 822 | 610–3768 | |
| CD4+ T cells (%) | All | 47.10 | 0.97 | 46.5 | 7.90 | 34.00–65.00 |
| Male | 46.18 | 1.63 | 45.00 | 8.47 | 34.00–63.00 | |
| Female | 47.74 | 1.20 | 48.00 | 7.53 | 34.00–65.00 | |
| CD8+ T cells (cells/μl) | All | 1553 | 89 | 1494 | 736 | 422–4154 |
| Male | 1545 | 119 | 1494 | 676 | 423–2927 | |
| Female | 1516 | 122 | 1320 | 793 | 518–4154 | |
| CD8+ T cells (%) | All | 40.40 | 0.87 | 40.00 | 7.13 | 25.00–56.00 |
| Male | 40.48 | 1.37 | 39.00 | 7.14 | 28.00–56.00 | |
| Female | 40.35 | 1.15 | 40.00 | 7.22 | 25.00–55.00 | |
| B cells (cells/μl) | All | 1308 | 113 | 1114 | 926 | 259–4808 |
| Male | 1181 | 132 | 1063 | 751 | 259–2817 | |
| Female | 1319 | 159 | 1006 | 1021 | 298–4804 | |
| B cells (%) | All | 20.87 | 0.87 | 20.00 | 7.12 | 5.00–44.00 |
| Male | 19.77 | 1.09 | 20.00 | 5.70 | 10.00–31.00 | |
| Female | 21.64 | 1.27 | 21.00 | 7.94 | 5.00–44.00 | |
| NK cells (cells/μl) | All | 765 | 69 | 527 | 557 | 89–2619 |
| Male | 782 | 96 | 526 | 546 | 89–2286 | |
| Female | 725 | 84 | 552 | 549 | 114–2619 | |
| NK cells (%) | All | 12.21 | 0.51 | 12.00 | 4.21 | 3.00–22.00 |
| Male | 12.96 | 0.85 | 13.00 | 4.44 | 3.00–22.00 | |
| Female | 11.69 | 0.64 | 11.00 | 4.02 | 3.00–22.00 | |
| NKT cells (cells/μl) | All | 311 | 19 | 265 | 162 | 52–730 |
| Male | 326 | 29 | 285 | 163 | 52–624 | |
| Female | 299 | 25 | 252 | 162 | 78–730 | |
| NKT cells (%) | All | 5.40 | 0.33 | 5.00 | 2.74 | 1.00–12.00 |
| Male | 5.92 | 0.49 | 6.00 | 2.58 | 1.00–11.00 | |
| Female | 5.05 | 0.45 | 5.00 | 2.82 | 1.00–12.00 |