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. 2024 May 10;45:101977. doi: 10.1016/j.tranon.2024.101977

Fig. 7.

Fig 7

HMGB2 factor promotes cell proliferation and inhibits apoptosis.(A)Effect of HMGB2 siRNA on cell proliferation.Cells were detected by staining with DAPI (blue), and the proliferating cells were recognized by staining with EdU (green). (B)Effect of HMGB2 overexpression on cell apoptosis.Cells were detected by staining with DAPI (blue), and the apoptosis cells were recognized by staining with TUNEL (green).(C-D)Percentages of EdU-positive cells were graphed with Histogram.(E-F)Percentages of TUNEL-positive cells were graphed with Histogram.CCK-8 assays were carried out in HMGB2 knockdown cells (G-H) and overexpression cells (I-J) after treated with doses of 0 and 6 Gy. *p < 0.05, **p < 0.01, ***p < 0.001,****p < 0.0001.