Table 5.
Univariable Logistic and Multivariable Cox regression analysis for prognosis of HCC.
| Variable | Threshold | Univariable |
Multivariable |
||
|---|---|---|---|---|---|
| P value | HR (95 %CI) | P value | HR (95 %CI) | ||
| RBP4 | 14.06 μg/mL | 0.001 | 0.090 (0.023∼0.359) | 0.005 | 0.447 (0.256∼0.708) |
| AFP | 25 ng/mL | <0.001 | 44.812 (11.878∼169.057) | <0.001 | 7.193 (4.464∼11.592 |
| Metastasis | 0.008 | 8.758 (1.742∼44.044) | 0.002 | 2.396 (1.376∼4.173) | |
| AST/ALT | 1 | 0.002 | 9.204 (2.310∼36.683) | <0.001 | 3.176 (1.732∼5.823) |
| Treatment | 0.143 | ||||
| Surgery | 0.041 | 5.947 (1.074∼32.919) | 0.766 | 0.908 (0.481∼1.714) | |
| Intervention | 0.070 | 7.112 (0.849∼59.555) | 0.017 | 2.085 (1.139∼3.819) | |
| Others | 0.187 | 2.768 (0.610∼12.548) | 0.185 | 0.688 (0.395∼1.196) | |
| Age | 0.875 | ||||
| Gender | 0.569 | ||||
| HBsAg | 0.5 ng/ml | 0.112 | |||
| A/G | 1.3 | 0.002 | 0.123 (0.032∼0.477) | 0.107 | |
| ADA | 22 U/L | 0.494 | 0.003 | 1.948 (1.249∼3.037) | |
| TP | 60 g/L | 0.916 | |||
| CA724 | 6 U/mL | 0.800 | |||
| CA199 | 37 U/mL | 0.111 | |||
| CA153 | 28 U/mL | 0.590 | 0.021 | 1.814 (1.094∼3.008 | |
| CA125 | 35 U/mL | 0.474 | |||
RBP4, retinol-binding protein 4; AFP, alpha-fetoprotein; AST, alanine transaminase; ALT, aspertate transaminase; HBsAg, hepatitis Bs antigen; A/G, albumin/globulin; ADA, adenosine deaminase; TP, total protein; CA724, carbohydrate antigen 724; CA199, carbohydrate antigen 199; CA153, carbohydrate antigen 153; CA125, carbohydrate antigen 125.