Fig. 2.

Protein kinases are intimately tied to each essential event of oocyte activation. Protein kinases and phosphorylation events have been directly implicated in transducing the calcium (Ca²⁺) signal into many of the necessary activation events required for successful fertilization. Such events encompass a swift block to polyspermy, cortical granule exocytosis, polar body extrusion, pronuclear development, plasma membrane reorganization, recruitment of maternal mRNAs, DNA repair and resumption of the cell cycle (See Table 1) (Adapted from [85])