Fig. 6.

The alternative route. a In polarized epithelial cells, the intercellular bridge containing ciliary proteins forms at the apical cell surface during cytokinesis. b When abscission occurs, one of the two daughter cells inherits the midbody remnant, which localizes apically at the cell periphery, near the tight junctions. c The remnant subsequently moves over the apical surface towards the centrosome, which is docked at the center of the apical membrane. d When the midbody meets the centrosome, the initiation of primary cilium assembly is facilitated. The entire process of primary cilium formation takes place in the plasma membrane