Fig. 4.
Retinoic acid inhibits the expression of members of the MYOD gene family, but preserves the expression of the determination genes PAX7 and PAX3. RT-qPCR analysis of the expression of myogenic determination and differentiation genes in human myoblasts incubated or not (ctrl) with 10−7M RA for 48 h. p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***). Data are shown as mRNA levels relative to the expression in Ctrl/non-treated cells at each timepoint, which was set at 1