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. 2017 Feb 15;74(12):2239–2261. doi: 10.1007/s00018-017-2469-1

Table 1.

List of miRNA target databases with experimentally validated targets

Database name Number of entry Version/year Implementation back/front end Reference
TarBase

miRNA–gene

interactions:65 814

Species :24

Paper curate: 10,000

TarBase (2006)

Tarbase 5 (2008)

Tarbase 6.0 (2012)

TarBase (2014)

Sql Server

PHP, Apache

http://diana.imis.athenainnovation.gr/DianaTools/index.php?r=tarbase/index
miRecords

miRNA-gene

interaction: 2705

miRNA: 664

gene:1907 from 9 animal

Curated from low

through put experiment:2028

miRecords (2008)

last updated

April 2013

MySQL, Fedora

Core 6 Linux

PHP project

on Apache 2.0

http://mirecords.biolead.org/
miRGator

Mature miRNA: 1856

Validated target:4745

Predicted target :6 218 792

miRGator (2008)

miRGator (2011)

miRGator (2013)

MySQL

Java script

J-Query

http://mirgator.kobic.re.kr/

http://genome.ewha.ac.kr/miRGator/

miRWalk 858,750,070 interactions between 11,748 miRNAs and 308,700 genes

miRwalk 1.0 (2010)

miRWalks2.0 (2014)

MySQL, JavaScript

Perl and BioPerl Scripts, bw GRID (High Performance Cluster)

http://www.umm.uni-heidelberg.de/apps/zmf/mirwalk/
miRTarBase

Species: 18

Target genes: 22,563

miRNAs: 3786

miRNA–target interactions: 366,181 Articles: 4966

miRTarBase 1.0 (2010)

miRTarBase 4.0 (2014)

miRTarBase 5.0(2015)

miRTarBase 6.0(2016)

MySQL

PHP

http://mirtarbase.mbc.nctu.edu.tw/index.php
miRSel

Human (2112 pairs)

Mouse (895 pairs)

Rat (231pairs)

Other organism: (452 pairs)

miRSel (2010)

JAVA (JDK 1.6, ZKoss framework)

Tomcat v 6.0

http://services.bio.ifi.lmu.de/mirsel/
starBase

miRNA-circRNA: 9000

miRNA-pseudogene: 16 000

protein–RNA: 285 000

StarBase (2011)

Starbase (2014)

MySQL

PHP on Apache

http://starbase.sysu.edu.cn
PMTED

miRNA:1897

Target: 5449

Species:12

Experiment:311

Assay:3492

PMTED (2013)

MySql

PHP

HTML

http://pmted.agrinome.org/
ComiRNet

5 million MTIs

miRNA: 934

mRNA:30,835

biclusterhierarchies:15

ComiRNet(2015)

PostgreSql

Play2.2 framework runs on server

Netty (netty.io)

http://www.comirnet.di.uniba.it
MtiBase

Gene: 15,546

miRNA: 4420

4 400 000 CDS -

470 000 5′UTR

miRNA target sites

SNP influence 290,000 CDS and 28,000 5′UTR miRNA target sites

MtiBase(2015)

MySql

PHP

http://mtibase.sysu.edu.cn