Fig. 2.

Conditionally disordered proteins stabilized by chemically specific binding events. a Nucleocapsid-binding (foot) domain from the mumps virus RdRp (PDB ID: 3BBZ). b B. subtilis RNAse P (PDB ID: 1A6F), with the sulfate ion responsible for structure induction shown in grey. c Third WW domain of human NEDD4-1 (PDB ID: 4N7F). d LEF-1 HMBG domain (PDB ID: 2LEF) bound to DNA. e ET-like domain of human AF9 in complex with AF4 (PDB ID: 2LM0). The ordered part of AF4 (amino acids 761–775) is displayed in grey. f Brinker nuclear repressor (PDB ID: 2GLO) bound to DNA. The program UCSF chimera [130] was used to generate this figure and Fig. 3