Table 1.

Two types of mosaic manifestations of Hailey–Hailey disease

	Clinical manifestation	Family history	Mutation type	References
Type 1 segmental HHD	Segmental distribution of skin lesions	No	Postzygotic de novo mutation	[19]
Type 2 segmental HHD	Rather severely affected segmental lesions being superimposed on typical nonsegmental skin lesions	Yes	A germline mutation in combination with somatic loss of heterozygosity	[18, 21]