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. 2024 May 21;22(5):e3002625. doi: 10.1371/journal.pbio.3002625

Table 1. Summary of body louse infection experiments with Y. pestis KIM6+(pmCherry).

Experiment # Y. pestis CFU/ml in the infectious blood meal Total # of lice (n) Infection rate (day 7 post-infection) Y. pestis cultured from feces (days 3–7) Transmission of Y. pestis (days 3–7) Detection of body lice with PG infection (days 3–7)
Bacteremia level >108 CFU/ml
1* 4.3 × 108 40 40% + + +
2* 5.8 × 108 40 60% + + +
3* 3.5 × 108 40 80% + + +
4 4.5 × 108 46 71% + + +
5 2.6 × 108 44 40% + + +
Average 4.1 × 108 42 58% + + +
Bacteremia level 107–108 CFU/ml
1 2.2 × 107 40 29% - + +
2 1.3 × 107 39 60% + + +
3 2.3 × 107 45 40% + + +
Average 1.9 × 107 41 43% + + +
Bacteremia level 106–107 CFU/ml
1 2.1 × 106 38 60% + - -
2 3.2 × 106 41 20% + - -
3 1.6 × 106 40 22% + - -
Average 2.3 × 106 40 34% + - -
Bacteremia level 105–106 CFU/ml
1 1.4 × 105 32 20% + - -
2 2.4 × 105 43 20% + - -
3 1.2 × 105 40 11% + - -
Average 1.7 × 105 38 17% + - -
Bacteremia level 104–105 CFU/ml
1 3.0 × 104 43 0% - - -
2 2.1 × 104 38 0% - - -
3 1.2 × 104 40 11% + - -
Average 2.1 × 104 40 4% +/- - -

* Data from experiments shown in Fig 1. All louse infections used the delayed transfer infection protocol (Fig 1A).