Table 1. Summary of body louse infection experiments with Y. pestis KIM6+(pmCherry).
Experiment # | Y. pestis CFU/ml in the infectious blood meal | Total # of lice (n) | Infection rate (day 7 post-infection) | Y. pestis cultured from feces (days 3–7) | Transmission of Y. pestis (days 3–7) | Detection of body lice with PG infection (days 3–7) |
---|---|---|---|---|---|---|
Bacteremia level >108 CFU/ml | ||||||
1* | 4.3 × 108 | 40 | 40% | + | + | + |
2* | 5.8 × 108 | 40 | 60% | + | + | + |
3* | 3.5 × 108 | 40 | 80% | + | + | + |
4 | 4.5 × 108 | 46 | 71% | + | + | + |
5 | 2.6 × 108 | 44 | 40% | + | + | + |
Average | 4.1 × 108 | 42 | 58% | + | + | + |
Bacteremia level 107–108 CFU/ml | ||||||
1 | 2.2 × 107 | 40 | 29% | - | + | + |
2 | 1.3 × 107 | 39 | 60% | + | + | + |
3 | 2.3 × 107 | 45 | 40% | + | + | + |
Average | 1.9 × 107 | 41 | 43% | + | + | + |
Bacteremia level 106–107 CFU/ml | ||||||
1 | 2.1 × 106 | 38 | 60% | + | - | - |
2 | 3.2 × 106 | 41 | 20% | + | - | - |
3 | 1.6 × 106 | 40 | 22% | + | - | - |
Average | 2.3 × 106 | 40 | 34% | + | - | - |
Bacteremia level 105–106 CFU/ml | ||||||
1 | 1.4 × 105 | 32 | 20% | + | - | - |
2 | 2.4 × 105 | 43 | 20% | + | - | - |
3 | 1.2 × 105 | 40 | 11% | + | - | - |
Average | 1.7 × 105 | 38 | 17% | + | - | - |
Bacteremia level 104–105 CFU/ml | ||||||
1 | 3.0 × 104 | 43 | 0% | - | - | - |
2 | 2.1 × 104 | 38 | 0% | - | - | - |
3 | 1.2 × 104 | 40 | 11% | + | - | - |
Average | 2.1 × 104 | 40 | 4% | +/- | - | - |