Fig 5. Uncertainty quantification and sensitivity analysis for [K⁺]_se(t) under physiological conditions.

The uncertainty level on input parameters was fixed at $\widehat{\sigma }=5\%$. (A) Mean ($\mathbb{E}$) and 90% prediction interval (I_0.9) for [K⁺]_se(t) evaluated at each time-step. (B-D) Total order Sobol’ indices ($S_{T_i}$), weighted Total order Sobol’ indices ($S_{T_i}^W$), and generalized Total order Sobol’ indices (${\mathfrak{S}}_{T_i}$) over time for the five uncertain parameters (different colors).