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. 2016 Mar 21;73(18):3583–3597. doi: 10.1007/s00018-016-2182-5

Fig. 6.

Fig. 6

The effect of aminochrome on substantia nigral mitochondria. The ultrastructure of mitochondria determined using transmission electron microscopy revealed that aminochrome induces mitochondria damage (black arrow head; b) in comparison with control animals with normal mitochondria (white arrow head; a). A significant increase in the number of damaged mitochondria per nm2 was observed when we count the number of damaged mitochondria per normal mitochondria and plotted in c. Scale bar is 500 nm. The significance was measured with unpaired Student’s t test (*P < 0.05)