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Transmission electron micrographs of a untreated Enterobacter cloacae NCTC 1005 and b cells of the same strain treated with 12.5 µg/mL (0.83×MIC) trimethoprim for 4 h. Many of the bacterial cells have developed intracellular vacuoles following treatment. Bar 1 µm.
Images from [195] by permission of the Journal of Medical Microbiology (MicroSoc)
