Fig. 3.

Local and remote regulation of IPCs in the brain. The IPCs are regulated by sNPF and corazonin from the DLP (dorsal lateral peptidergic) neurons that send processes to the IPC dendrites in the pars intercerebralis. These DLPs express sNPF and corazonin, the fructose receptor Gr43b and a GPCR for diuretic hormone 31 (DH₃₁), a peptide that could be released from the intestine. The IPCs express DILP2, 3 and 5, drosulfakinin (DSK) and a number of GPCRs (in red text), as well as the insulin receptor (dInR). The GPCRs are discussed and acronyms explained in the text. The DILPs are released from the peripheral axon terminations (not shown) of the IPCs; asterisks where these axons originate in the brain and project to the corpora cardiaca, aorta and anterior gut structures. MB mushroom bodies (shown for orientation)