Table 1.
Somatometric, metabolic and biochemical parameters of the two study groups
| Parameters | Group LA (mean ± SE) | Group HA (mean ± SE) | P value (LA vs. HA comparison)a |
|---|---|---|---|
| Body weight at baseline (g) | 197.0 ± 4.3 | 199.7 ± 4.2 | 0.851 |
| Body weight at 3 months (g) | 206.0 ± 4.5 | 193.3 ± 4.4 | 0.050 |
| Serum glucose (mg/dL) | 119.0 ± 7.9 | 112.2 ± 6.6 | 0.548 |
| AGEs (U/mL) | 4.48 ± 0.24 | 6.72 ± 0.26 | <0.0001* |
| Fructosamine (μmol/L) | 201.2 ± 33.1 | 159.4 ± 8.8 | 0.663 |
| Insulin (μU/mL) | 1.22 ± 0.04 | 1.96 ± 0.14 | <0.0001* |
| CRP (μg/mL) | 176.3 ± 10.9 | 356.3 ± 11.1 | <0.0001* |
| Total cholesterol (mg/dL) | 36.8 ± 2.0 | 45.4 ± 3.0 | 0.014* |
| Serum triglycerides (mg/dL) | 44.6 ± 1.3 | 54.6 ± 3.0 | 0.004* |
Values are presented as mean ± standard error (SE) of mean
LA low-AGE-fed animals, HA high-AGE-fed animals
aDerived from Mann–Whitney Wilcoxon test for independent samples (level of statistical significance 0.007, due to the Bonferroni correction)
* Denotes statistically significant differences