Fig. 2.

Biomechanical stimuli and redox signaling in endothelial cells. WSS wall shear stress, Nrf2 nuclear factor erythroid 2-related factor 2, Keap1 kelch-like ECH-associated protein 1, TXNIP thioredoxin-interacting protein, ROS reactive oxygen species, eNOS endothelial nitric oxide synthase, PKCζ protein kinase Cζ, NF-κB nuclear factor κB, ECM extracellular matrix