Table 2. Clinical and laboratory characteristics, and corticosteroid doses at the start and 6 months and 1 year after the start of treatment (cyclophosphamide + methylprednisolone + methotrexate), of 5 patients with juvenile rheumatoid arthritis and juvenile spondyloarthropathy.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months after start of treatment | 0 | 6 | 12 | 0 | 6 | 12 | 0 | 6 | 12 | 0 | 6 | 12 | 0 | 6 | 12 |
| Number of active joints | 1 | 1 | 2 | 8 | 2 | 1 | 5 | 1 | 1 | 3 | 7 | 2 | 5 | 3 | 3 |
| Steinbrocker functional class | II | I | IV | II | IV | II | III | II | II | II | |||||
| Hb, g/100 ml | 9.8 | 12.7 | 13.0 | 7.3 | 9.8 | 9.7 | 10.1 | 9.6 | 10.2 | 12.8 | 8.2 | 9.2 | 8.2 | 9.7 | 8.8 |
| Htc, % | 31 | 40.0 | 39.7 | 24 | 30 | 31.4 | 34 | 32 | 31 | 41 | 28 | 29 | 27 | 32 | 30.5 |
| WBC, x1000/cm2 | 9.7 | 11.3 | 6.4 | 15.0 | 16.4 | 10.8 | 9.8 | 4.4 | 6.9 | 11.3 | 12.4 | 11.0 | 5.5 | 5.4 | 3.5 |
| Platelets, x1000/cm2 | 117 | 442 | 418 | 762 | 704 | 599 | 519 | 290 | 352 | 403 | 709 | 303 | 240 | 280 | 241 |
| ESR, mm/hour | 71 | 22 | 22 | 125 | 91 | 60 | 40 | 4 | 48 | 57 | 26 | 45 | 54 | 12 | 14 |
| CS, mg/kg/day | 0.28 | 0.17 | 0.14 | 0.41 | 0.15 | 0 | 0.21 | 0.20 | 0.08 | 0.34 | 0.17 | 0.09 | 0.20 | 0 | 0 |
Hb = hemoglobin; Htc = hematocrit; WBC = white blood cell count; ESR = Westergren erythrocyte sedimentation rate; CS = corticosteroids.