Table 2.
TRAEs
| Toxicity (selected TRAEsa) | Grade 1/2, n(%) | Grade 3/4, n (%) | Any grade, n (%) |
|---|---|---|---|
| Arthralgia | 9 (26) | 1 (3) | 10 (29) |
| Diarrhea | 7 (20) | 0 (0) | 7 (20) |
| Dyspnea | 7 (20) | 1 (3) | 8 (23) |
| Fatigue | 10 (29) | 0 (0) | 10 (29) |
| Gastrointestinal disorders | 7 (20) | 0 (0) | 7 (20) |
| Myalgia | 4 (11) | 0 (0) | 4 (11) |
| Nausea/vomiting | 8 (23) | 0 (0) | 8 (23) |
| Nervous system disorders | 5 (14) | 0 (0) | 5 (14) |
| Pain | 9 (26) | 1 (3) | 10 (29) |
| Pruritis | 10 (29) | 0 (0) | 10 (29) |
| Rash | 6 (17) | 1 (3) | 7 (20) |
| Skin disorders | 5 (14) | 0 (0) | 5 (14) |
aShown are TRAEs of any grade that occurred in more than 10% of patients.