Extended Data Fig. 7. Identification of initial baseline characteristics that best predicted responder status.
This analysis included sequential logistic regression models whereby participants were binarized into two groups: above or below a single numerical threshold78,79. Odds ratios were then calculated, which reflected the odds of being a responder based on sequential thresholds for each outcome measure included in the primary and secondary effectiveness end points. The sequential models were halted when the odds ratio crossed 1 (black traces), indicating a threshold above which participants demonstrated positive odds of responding to ARCEX Therapy. This analysis revealed cutoffs for ISNCSCI-UEMS (cutoff = 25), Grasp force (cutoff = 100N), Pinch force (cutoff = 25N), CUE-T (cutoff = 40), ISNCSCI Sensory Score (cutoff = 120), ISNCSCI Upper Extremity Sensory Score (cutoff = 40), and GRASSP-Sensibility score (cutoff = 15).