Figure 4.

(A) Correlation between raw DDIR signature score and CXCL10 RNA expression (FPKM) in the GO2 adenocarcinoma population. Boxplot denotes the distribution of expression values for the DDIR-positive and -negative samples in the cohort. (B) Overall survival in the GO2 adenocarcinoma population according to CXCL10 RNA expression (FPKM). Low—bottom 25%, middle—25%–75%, high—top 25%. (C) Cox regression analysis for overall survival incorporating CXCL10 RNA expression group. ∗indicates P-value <0.05. (D) Correlation between raw DDIR signature score and CXCL10/CCL5 RNA expression (FPKM) signature in the GO2 adenocarcinoma population. Boxplot denotes distribution of values for DDIR-positive and -negative in the cohort.

AIC, Akaike's Information Criterion; DDIR, DNA damage immune response; ECOG, Eastern Cooperative Oncology Group; GOJ, gastroesophageal junction.