Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 May 21;14:11637. doi: 10.1038/s41598-024-62222-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Physiological and functional changes in mice following sublethal exposure to ricin toxin. Mice were intranasally intoxicated with ricin (1.7 µg/kg body weight) and monitored for 30 days. (A) Morbidity as depicted by body weight loss following intoxication (n = 10). (B) Activity profile of mice according to voluntary wheel running. Base line was determined as the average running distance of each animal from 5 days prior to intoxication (represented as 100% on day −1). Then, the mice were exposed to ricin (day 0) and their activity was further recorded for 30 days (n = 11). (C) Lung compliance of ricin intoxicated mice over 30 days. Each dot represents one animal. Data are represented as means ± SEM. **P < 0.001, ***P < 0.0001, n.s., not significant, in comparison to non-intoxicated mice.