Skip to main content
. 2024 May 10;18:e00236. doi: 10.1016/j.mec.2024.e00236

Fig. 5.

Fig. 5

Analysis of MetX and MetX-C5. (A) Sequence alignment of MetX CG with MetX of Leptospira interrogans (LI), Mycolicibacterium smegmatis (MS), and Mycobacteroides abscessus (MA). Green arrows show the position of the R46H and L315P mutations. Sequence alignment was done with JalView version 2.11.3.2. (B) The structure of wild-type MetX CG and the MetX-C5 with the two mutations are shown in red color. (C) Superposition of wild-type (gray) and L315P MetX mutant (light blue). The hydrogen bond in the L315P variant between His341 and Asp311 has a shorter length (3.4 Å) relative to the wild-type protein (3.8 Å).