Table 1.
Clinical characteristics on patients with DM1.
| Total group (n = 128) | Childhood (n = 12) | Juvenile (n = 28) | Adult (n = 67) | Late (n = 21) | |
|---|---|---|---|---|---|
| Age | 48 (14) | 38.8 (10.7) | 39.1 (13.1) | 47.6 (11) | 66.1 (10.8) |
| Sex | 66 F, 62 M | 6 F, 6 M | 16 F, 12 M | 35 F, 32 M | 9 F, 12 M |
| Durationa | 20 (11) | 31.1 (10.2) | 25.8 (12.1) | 17.9 (10.1) | 12.1 (6.7) |
| CNS-related | |||||
| disorderb8 (6 %) | 0 (0 %) | 1 (8 %) | 2 (3 %) | 5 (24 %) | |
| MIRS | 3.36 (1) | 3.9 (0.7) | 3.5 (0.9) | 3.5 (0.9) | 2.6 (2) |
| FDSS | 8.89 (3.74) | 40.5 (11.0) | 38 (10.1) | 38.1 (11.1) | 35 (11.1) |
| EQ-5Dc | 0.8 (0.9) | 0.3 (0.5) | 0.6 (0.9) | 0.9 (0.9) | 0.7 (0.7) |
Note. DM1 = Myotonic Dystrophy type 1, MIRS = Muscular Impairment Rating Scale, FDSS = Fatigue and Daytime Sleepiness Scale.
a
disease duration (years).
b
other disorders possibly related to cerebral dysfunction.
c
EQ-5D rating on anxiety and depression (for details, see Supplementary data, Table 4 on severity level). Results are presented as mean (sd) when appropriate.