The impact of PAC on expression of signaling pathways associated with EMT and MMP in RCC. (A) Representative images and quantitative assessment of (B) E-cadherin/β-actin, (C) Vimentin/β-actin, and (D) N-cadherin/β-actin of EMT signaling pathways in RCC by Western blot. (E) Representative images and quantitative analysis of (F) MMP-2/β-actin, (G) MMP-9/β-actin, and (H) TIMP-1/β-actin of MMP signaling pathways in RCC after by Western blot. Mean ± SD (n = 5). *p < 0.05, **p < 0.01 and ***p < 0.001 vs. 0 μM PAC group.