Table 3.
Univariate and multivariate logistics regression analyses of CBC-derived systemic-inflammatory indices associated with 90-day functional outcome.
| 90-day functional outcome |
|||||||
|---|---|---|---|---|---|---|---|
| mRS 0–2 (n = 251) | mRS 3–6 (n = 231) | OR (95%CI) | P | aOR (95%CI)a | P | aPb | |
| Admission, median (IQR) | |||||||
| Neutrophil, × 109/L | 6.33(4.99–8.28) | 6.76(4.62–8.99) | 1.046(0.988–1.107) | 0.126 | 1.091(1.005–1.184) | 0.037 | 0.407 |
| Monocyte, × 109/L | 0.41(0.32–0.52) | 0.39(0.28–0.52) | 0.911(0.619–1.340) | 0.635 | 0.976(0.624–1.528) | 0.915 | Ns |
| Lymphocyte, × 109/L | 1.36(1–1.87) | 1.18(0.86–1.65) | 0.836(0.680–1.029) | 0.091 | 0.862(0.679–1.096) | 0.225 | Ns |
| Platelet, × 109/L | 201(173–243.5) | 205(165–247.5) | 1.000(0.997–1.003) | 0.929 | 1.003(0.999–1.006) | 0.121 | Ns |
| NLR | 4.99(3.02–7.48) | 5.7(3.07–8.99) | 1.033(1.002–1.065) | 0.04 | 1.031(0.997–1.065) | 0.074 | 0.815 |
| MLR | 0.29(0.22–0.4) | 0.32(0.21–0.44) | 1.064(0.789–1.434) | 0.685 | 1.041(0.725–1.495) | 0.828 | Ns |
| PLR | 149.2(108.5–212.4) | 167.2(111.5–243.2) | 1.001(1.000–1.002) | 0.188 | 1.001(0.999–1.003) | 0.22 | Ns |
| PNR | 31.05(23.85–42.82) | 31.41(21.62–41.95) | 0.995(0.987–1.003) | 0.242 | 0.996(0.987–1.005) | 0.423 | Ns |
| SII | 960.2(543.6–1628) | 1165(590.7–1827) | 1.000(1.000–1.000) | 0.112 | 1.000(1.000–1.000) | 0.066 | 0.727 |
| SIRI | 1.78(1.14–3.31) | 1.97(1.11–3.54) | 1.008(0.980–1.036) | 0.595 | 1.007(0.975–1.041) | 0.654 | Ns |
| AISI | 361(216.2–633.5) | 393.3(205–769.2) | 1.000(1.000–1.000) | 0.878 | 1.000(1.000–1.000) | 0.656 | Ns |
| Day 1, median (IQR) | |||||||
| Neutrophil, × 109/L | 7.36(5.7–9.03) | 8.43(6.94–10.83) | 1.141(1.072–1.215) | <0.001 | 1.128(1.040–1.223) | 0.004 | 0.045 |
| Monocyte, × 109/L | 0.44(0.32–0.55) | 0.41(0.27–0.59) | 0.665(0.297–1.491) | 0.323 | 1.268(0.419–3.833) | 0.674 | Ns |
| Lymphocyte, × 109/L | 1.16(0.79–1.5) | 0.88(0.61–1.23) | 0.806(0.602–1.081) | 0.15 | 0.889(0.728–1.086) | 0.251 | Ns |
| Platelet, × 109/L | 207(173.5–243) | 202(161–243) | 0.999(0.996–1.001) | 0.35 | 1.002(0.999–1.006) | 0.173 | Ns |
| NLR | 6.65(4.26–9.42) | 10.05(5.93–15.06) | 1.086(1.053–1.119) | <0.001 | 1.061(1.022–1.102) | 0.002 | 0.024 |
| MLR | 0.38(0.27–0.55) | 0.48(0.29–0.66) | 2.861(1.537–5.326) | 0.001 | 2.382(1.010–5.617) | 0.047 | 0.517 |
| PLR | 180(136.4–251) | 219.2(152.9–328.6) | 1.003(1.002–1.004) | <0.001 | 1.002(1.001–1.004) | 0.005 | 0.058 |
| PNR | 28.66(21.78–36.73) | 22.68(18.03–30.7) | 0.981(0.968–0.995) | 0.008 | 0.994(0.983–1.006) | 0.324 | Ns |
| SII | 1339(865.9–1998) | 1878(1154–3019) | 1.000(1.000–1.000) | <0.001 | 1.000(1.000–1.000) | 0.001 | 0.009 |
| SIRI | 2.64(1.83–4.64) | 3.92(2.02–6.24) | 1.105(1.048–1.165) | <0.001 | 1.092(1.018–1.172) | 0.014 | 0.157 |
| AISI | 537.1(347.6–909.4) | 829.5(370.6–1296) | 1.000(1.000–1.001) | 0.001 | 1.001(1.000–1.001) | 0.003 | 0.035 |
Note.
Abbreviations: OR, odds ratio; aOR, adjusted odds ratio; aP, adjusted p value; CI, confidence interval; IQR, interquartile range; ns, not significant.
a
adjustment for age, sex, diabetes mellitus, coronary heart disease, drinking, prior stroke, antiplatelet use, admission NIHSS and ASPECTS scores, groin puncture-to-recanalization time, anesthesia type, the number of passes, mTICI, and sICH.
b
Bonferroni correction.