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. 2024 Apr 19;15:1352671. doi: 10.3389/fendo.2024.1352671

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Copyright © 2024 Li, Yang, Li, Zhang, Li and Lv

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The multisystemic impact of osteoarthritis: a comprehensive overview. OA manifests symbiotic relationships with several systemic diseases, thereby giving rise to numerous comorbidities. These include skeletal-muscular diseases, cardiovascular diseases, endocrine and metabolic diseases, nervous system diseases, mental diseases, and solid cancers. Templates adapted to create this figure are freely available from Servier Medical Art (https://smart.servier.com/), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/).