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. 2024 May 22;24:179. doi: 10.1186/s12876-024-03263-2

Table 2.

Inclusion and exclusion criteria

Inclusion criteria
1.     Age ≥ 18 years old
2.     Biopsy-proven IBD
3.     Impaired quality of life: Short IBD Questionnaire (SIBDQ) < 60
4.     Symptoms: at least “some of the time” abdominal pain or bowel symptoms on SIBDQ
5.     Fluent in English
6.     Physically able to travel to study visits, within 1.5 h drive of study location
Exclusion criteria
Health:
1.     Current ileostomy, colostomy, ileoanal pouch, ileorectal anastomosis, or short bowel syndrome
2.     Other significant chronic physical disease (e.g., uncontrolled diabetes, advanced liver disease, cancer, kidney failure, uncontrolled cardiovascular disease, seizures, light-triggered migraines).
3.     Has a pacemaker or defibrillator (potential interference from Fitbit device)
4.     Retinal pathology, cataracts, glaucoma, colorblindness
5.     Lifetime history of psychotic or bipolar disorders
6.     Suicidality in past 6 months
7.     Alcohol or substance use disorder in past 3 months (cannabis use ≤ 1/week ok)
8.     High risk for or diagnosed with obstructive sleep apnea and/or narcolepsy
9.     Severe hearing problem, cognitive impairment, not fluent in English
10.  Pregnant, trying to get pregnant, or breastfeeding
11.  Has a child or pet at home that disturbs sleep often
12.  Pending medical leave application at work, pending legal case/litigation
13.  Working shiftwork that affects sleep
14.  Recent (< 1 month) travel outside Eastern Time Zone
15.  Participating in another research study
Medications:
17.  Taking photosensitizing medications to blue/green light (including methotrexate, sulfasalazine, promethazine, prochlorperazine)
18.  Taking melatonin
19.  Unstable non-IBD medication use 30 days prior to or during study
20.  Change of ≥ 10 mg/day of steroid medications use 30 days prior to or during study
Light treatment:
21.  Average wake time is before 5:00am
22.  Unable to fit 1 h of light treatment into morning routine
23.  Previous use of light treatment device in the past year