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Platelet aggregation in whole blood incubated with ADP (0.1 μM). The blood was collected from mice, 24 h after pulmonary administration of either saline or diesel exhaust particles (DEP; 20 μg/mouse) with or without carnosol pretreatment (20 mg/kg) given 1 h earlier. Platelet aggregation was assessed by estimating the fall in single platelets, counted due to aggregation induced by ADP. Data are means ± SEM (n = 8). Statistical analysis was by Holm–Sidak's multiple comparisons test.
