Table 3.

Complications.

Groups related	Compendium	Examples
Ziconotide	Mental &nervous system	Poor analgesic efficacy [103,104]
		Depression [105,106]
		Aggravate suicidal tendency [106]
		Somnolence [91,80]
		Blurred vision
	Motor system	Dysarthria and shiver
		Vertigo [80], etc.
	Circulatory system	Hypotension [55,103]
		Peripheral edema [103]
	Digestive system	Worsen morphine-induced constipation [40]
		Nausea [91]
		Diarrhea [91,80]
	Urinary system	Impaired Renal function? [58]
Procedure	vascular injury [59], local infection, flaccid paraplegia/paraplegia [70,82], leakage of CSF [56,58], meningitis [82], spinal hematoma [77] and so on.
Device	Catheter dislocation &leakage [107], pump malfunction [[108], [109], [110]], etc.