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. Author manuscript; available in PMC: 2024 May 22.
Published in final edited form as: Exp Mol Pathol. 2017 May 25;102(3):515–521. doi: 10.1016/j.yexmp.2017.05.015

Figure 3. 1,25(OH)2D3 induces immunoregulatory cytokine and decreases pro-inflammatory cytokines expression in EAE.

Figure 3.

Splenocytes of 25(OH)2D3 treated and vehicle EAE mice were stimulated with PMA, ionomycin and Golgi Plug for 4 hours, stained, and analyzed by flow cytometry. Percentages of IFN-γ+, IL-17A+, GM-CSF+, IL-4+ and IL-10+ cells in gated CD4+ T cells were determined (A), and statistically analyzed (B). Data represent mean±SEM (n=5/group), *P< 0.05, **P< 0.01, and ***P< 0.001. One representative of three experiments is shown.