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. 2024 May 9;12:1375493. doi: 10.3389/fped.2024.1375493

Table 1.

MSCs therapy indications and infusion scheme.

Previous treatments Number of patients N (%) MSCs infusion scheme
aGVHD GC, ECP, RXL, MMF, infliximab, sirolimus 13 (43.3) 4 infusions on days: +1, +4, +11, +18
cGVHD GC, ECP, RXL 5 (16.7)
Graf failure 1–3 previous HSCT 2 (6.7) 2 infusions on days: +1 (co-infusion with HSCT), +15
Poor graft function Eltrombopag, CD34 boost 6 (20) 2 infusions on days: +1 (co-infusion with CD34 boost), +15
Hemorrhagic cystitis Cydofovir, intravesical: hyaluroic acid, E-aminocaproic acid/urokinase 4 (13.3) 3–4 infusions on days: +1, +7, +14, (+18)
All NA 30 NA

GC, glucocorticoids; ECP, extracorporeal photopheresis; RXL, ruxolitinib; MMF, mycophenolate; HSCT, hematopoietic stem cell transplant; aGVHD, acute graft versus host disease; cGVHD, chronic graft versus host disease; NA, not applicable.