Table 4.

Deaths and causes of death.

Patients	Diagnosis	MSCs indication	Maximun response to MSCs	Patient's clinical situation with respect to the indication that led to MSC therapy at last FU	Cause of death/months after last MSCs infusion
1	MDS	aGVHD	PR	Severe cGVHD	Respiratory failure: bronchiolitis obliterans/6
2a	B-Thal	aGVHD	PR	Severe cGVHD	Respiratory failure: alveolar hemorrhage/7
3	x-ALD	aGVHD	NR	aGVHD grade IV	Disease relapse/3
4	B-ALL	aGVHD	NR	aGVHD grade IV	Respiratory failure: alveolar hemorrhage/17
5	B-ALL	cGVHD	PR	Mild cGVHD	IFI/17
6	T-ALL	HC	PR	Grade 1 HC	Leukemia relapse/2
7	DKC	PGF	NR	PGF	Respiratory failure: complicated bacterial pneumonia, alveolar hemorrhage/54

MSD, myelodysplastic syndrome; B-Thal, Beta thalassemia major; ALL, acute lymphoblastic leukemia; ALD, x-linked adrenoleukodystrophy; DKC, Dyskeratosis congenita; aGVHD, acute graft versus host disease; cGVHD, chronic graft versus host disease; HC, hemorrhagic cystitis; PGF, poor graft function; LGI, lower gastrointestinal tract; PR, partial response; NR, no response; FU, follow-up; IFI, invasive fungal infection.

^a Also referred as patient 2 in Table 2.