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. 2014 Feb 11;16(10):832–839. doi: 10.1177/1098612X14520810

Table 2.

Summary of findings on post-mortem examination in five cats with hyaline degeneration

Macroscopic findings Microscopic findings: brain Microscopic findings: spinal cord
Cat 1 Hemorrhage – ventral brainstem/cervical SC AD, HyD (BA), thrombosis, WM degeneration (caudal medulla) AD (VSA) C3-C5, thrombosis, ventral funiculus WM degeneration
Cat 2 Hemorrhage – ventral brainstem/cervical SC (Figure 3) HyD (meninges), thrombosis (BA branch), leptomeningeal fibrosis, acute, chronic hemorrhage (medulla) (Figure 5c). WM degeneration cerebellar peduncle hemorrhage Cranial cervical SC, bilateral WM/GM necrosis
Cat 3 Red nodule (vascular ectasia [aneurysm]) – ventral C2 HyD (meninges), mixed perivascular/vascular inflammation AD (VSA), chronic perivascular hemorrhage, GM degeneration, hemorrhage, gliosis, HyD (C3)
Cat 4 Red nodules (vascular ectasia [aneurysm]) – ventral
C3–C5, L3–L4, medulla (Figure 4)
AD, HyD (BA branch), compression, midline shift, regional WM degeneration, necrosis, chromatolysis AD, HyD (VSA) C3–C5, L3, L4, thrombosis, compression (Figures 5a,b), WM degeneration, occasional necrosis, chronic hemorrhage, inflammation
Cat 5 Red nodules (vascular ectasia [aneurysm]) – C7–T1, L3 HyD (BA branches), mineralization, meningeal chronic inflammation and hemorrhage, focal cerebellar necrosis AD, HyD (VSA) C7–T1, L3, thrombosis, compression, ventral funiculi WM degeneration, gliosis, chromatolysis

SC = spinal cord; AD = aneurysmal dilation; HyD = hyaline degeneration; BA = basilar artery; WM = white matter; VSA = ventral spinal artery; GM = gray matter