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Mean thermal threshold (TT) in cats after subcutaneous injection of buprenorphine 0.02 mg/kg (AG6, orange, n = 3), 0.06 mg/kg (AG4, pink, n = 6), 0.12 mg/kg (AGs 2, 3 and 7, purple, n = 18) and 0.24 mg/kg (AG5, black, n = 6). Injection at time 0. Baseline TT at 0 is mean of five measurements taken before treatment. Shaded area is baseline TT in each group for visualisation. Error bars omitted for clarity; no statistical difference between groups – see text
