TABLE 1.

The correlation between different cancers and CD44.

Cancer type	Role of CD44 in cancer progress	References
Brain cancer	Poor prognosis, tumor progression, aggressive behavior	39 , 40 , 41
Head and neck cancer	Stemness, tumor progression	48 , 49
Breast cancer	Aggressive behavior, tumor progression, stemness, poor prognosis	56 , 57 , 58 , 59 , 60
Kidney cancer	Poor prognosis, aggressive behavior, tumor growth	65 , 66 , 67
Liver cancer	Cancer initiation, poor prognosis, stemness	72 , 73 , 74
Pancreatic cancer	Tumorigenicity, clinicopathological features, aggressive behavior	80 , 81 , 82
Gallbladder cancer	Stemness, aggressive behavior, tumor progression, poor prognosis	91 , 92 , 93 , 94
Esophageal cancer	Tumor progression, stemness, poor prognosis, aggressive behavior	97 , 98 , 99 , 101 , 102
Prostate cancer	Tumor progression, stemness, aggressive behavior	104 , 105 , 106 , 109
Gastrointestinal cancer	Tumor progression, stemness, aggressive behavior, CSCs self‐renewal characteristic tumorigenesis	114 , 115 , 116 , 117 , 119
Melanoma	Stemness, tumorigenesis, aggressive behavior	122 , 123 , 125
Squamous cell carcinoma	Aggressive behavior, stemness, tumorigenesis, tumor progression	128 , 129 , 130
Sarcoma	Tumor progression, stemness, aggressive behavior, poor prognosis	133 , 134 , 135 , 138 , 139