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Effects of trans-chalcone treatment on joint stiffness (A), flexion pain (B), mobility (C), and stance score (D) in CFA-injected rats. Values are presented as the mean with SEM (n = 6). Significance levels: ### indicates p < 0.001 in comparison to the normal control. * indicates p < 0.05, ** denotes p < 0.01, and *** represents p < 0.001 in comparison to the arthritis control. The statistical test used was a two-way ANOVA followed by the Dunnett test.
