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| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 NPI change from baseline at 6 months | 3 | 1039 | Mean Difference (IV, Fixed, 95% CI) | ‐0.84 [‐1.64, ‐0.05] |
| 2 NPI change from baseline at 1 year | 3 | 983 | Mean Difference (IV, Fixed, 95% CI) | ‐1.11 [‐2.10, ‐0.12] |
| 3 NPI change from baseline at 1 year (using random‐effects model) | 3 | 983 | Mean Difference (IV, Random, 95% CI) | ‐1.64 [‐3.45, 0.18] |
