Database/source	Search strategy	Notes
Specialized Register	statin* OR lipophilic OR hydrophilic
The Cochrane Library	1. statin*.tiabkw. 2. hydroxymethylglutaryl‐CoA Reductase Inhibitors/ (all subheadings) 3. 1 OR 2 4. Alzheimer‐disease/ all subheadings 5. exp dementia‐vascular/ all subheadings 6. creutzfeldt‐jakob‐syndrome/ all subheadings 7. kluver‐bucy‐syndrome/ all subheadings 8. lewy‐body‐disease/ all subheadings 9. pick‐disease‐of‐the‐brain/ all subheadings 10. Huntington‐disease/ all subheadings 11. delirium/ all subheading 12. wernicke‐encephalopathy/ all subheadings 13. (dement$ OR Alzheimer$).tiab. 14. (Lewy$ AND body$).tiab. 15. ((cognit$ OR memor$ OR mental) and (decline$ OR impair$ OR los$ OR deteriorate$)).tiab. 16. (chronic AND cerebrovascular).tiab. 17. ((organic brain syndrome) OR (organic brain disease)).tiab. 18. ((cerebr$ AND deteriorate$) OR (cerebr$ AND insufficien$)).tiab. 19. ((pick$ and disease) or (Creutzfeldt or JCD or CJD) or Huntington$ or Binswanger$ or Korsakoff$).tiab. 20. 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 21. 20 AND 4 22. limit 21 to (randomised controlled trial).pt.
MEDLINE (Ovid SP)	1. (statin$ OR lipophilic OR hydrophilic).mp. 2. (lovastatin OR simvastatin OR cervistatin OR atorvastatin OR rosuvastatin OR pravastatin OR fluvastatin).mp. 3. Hydroxymethylglutaryl‐CoA Reductase Inhibitors/ all subheadings 4. Alzheimer‐disease/ all subheadings 5. exp dementia‐vascular/ all subheadings 6. creutzfeldt‐jakob‐syndrome/ all subheadings 7. kluver‐bucy‐syndrome/ all subheadings 8. lewy‐body‐disease/ all subheadings 9. pick‐disease‐of‐the‐brain/ all subheadings 10. Huntington‐disease/ all subheadings 11. delirium/ all subheading 12. wernicke‐encephalopathy/ all subheadings 13. (dement$ OR Alzheimer$).mp. 14. (Lewy$ AND body$).mp. 15. ((cognit$ OR memor$ OR mental) and (decline$ OR impair$ OR los$ OR deteriorate$)).mp. 16. (chronic AND cerebrovascular).mp. 17. ((organic brain syndrome) OR (organic brain disease)).mp. 18. ((cerebr$ AND deteriorate$) OR (cerebr$ AND insufficien$)).mp. 19. ((pick$ and disease) or (Creutzfeldt or JCD or CJD) or Huntington$ or Binswanger$ or Korsakoff$).mp. 20. 1 OR 2 OR 3 21. 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 22. 20 AND 21 23. randomized controlled trial.pt. 24. controlled clinical trial.pt. 25. randomized.ab. 26. placebo.ab. 27. drug therapy.fs. 28. randomly.ab. 29. trial.ab. 30. groups.ab. 31. 23 OR 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30 32. humans.sh. 33. 31 AND 32 34. 22 AND 33
EMBASE (Ovid SP)	1. (statin$ OR lipophilic OR hydrophilic).mp. 2. (lovastatin OR simvastatin OR cervistatin OR atorvastatin OR rosuvastatin OR pravastatin OR fluvastatin).mp. 3. Hydroxymethylglutaryl‐CoA Reductase Inhibitors/ all subheadings 4. Alzheimer‐disease/ all subheadings 5. exp dementia‐vascular/ all subheadings 6. creutzfeldt‐jakob‐syndrome/ all subheadings 7. kluver‐bucy‐syndrome/ all subheadings 8. lewy‐body/ all subheadings 9. pick‐presenile‐dementia/ all subheadings 10. Huntington‐chorea/ all subheadings 11. delirium/ all subheading 12. wernicke‐encephalopathy/ all subheadings 13. (dement$ OR Alzheimer$).mp. 14. (Lewy$ AND body$).mp. 15. ((cognit$ OR memor$ OR mental) and (decline$ OR impair$ OR los$ OR deteriorate$)).mp. 16. (chronic AND cerebrovascular).mp. 17. ((organic brain syndrome) OR (organic brain disease)).mp. 18. ((cerebr$ AND deteriorate$) OR (cerebr$ AND insufficien$)).mp. 19. ((pick$ and disease) or (Creutzfeldt or JCD or CJD) or Huntington$ or Binswanger$ or Korsakoff$).mp. 20. 1 OR 2 OR 3 21. 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 22. 20 AND 21 23. randomized controlled trial.pt. 24. controlled clinical trial.pt. 25. randomized.ab. 26. placebo.ab. 27. drug therapy.fs. 28. randomly.ab. 29. trial.ab. 30. groups.ab. 31. 23 OR 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30 32. humans.sh. 33. 31 AND 32 34. 22 AND 33
CINAHL (Ovid SP)	1. (statin$ OR lipophilic OR hydrophilic).mp. 2. (lovastatin OR simvastatin OR cervistatin OR atorvastatin OR rosuvastatin OR pravastatin OR fluvastatin).mp. 3. Hydroxymethylglutaryl‐CoA Reductase Inhibitors/ all subheadings 4. Alzheimer‐disease/ all subheadings 5. exp dementia‐vascular/ all subheadings 6. creutzfeldt‐jakob‐syndrome/ all subheadings 7. kluver‐bucy‐syndrome/ all subheadings 8. lewy‐body‐disease/ all subheadings 9. pick‐disease‐of‐the‐brain/ all subheadings 10. Huntington‐disease/ all subheadings 11. delirium/ all subheading 12. wernicke‐encephalopathy/ all subheadings 13. (dement$ OR Alzheimer$).mp. 14. (Lewy$ AND body$).mp. 15. ((cognit$ OR memor$ OR mental) and (decline$ OR impair$ OR los$ OR deteriorate$)).mp. 16. (chronic AND cerebrovascular).mp. 17. ((organic brain syndrome) OR (organic brain disease)).mp. 18. ((cerebr$ AND deteriorate$) OR (cerebr$ AND insufficien$)).mp. 19. ((pick$ and disease) or (Creutzfeldt or JCD or CJD) or Huntington$ or Binswanger$ or Korsakoff$).mp. 20. 1 OR 2 OR 3 21. 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 22. 20 AND 21 23. randomized controlled trial.pt. 24. controlled clinical trial.pt. 25. randomized.ab. 26. placebo.ab. 27. drug therapy.fs. 28. randomly.ab. 29. trial.ab. 30. groups.ab. 31. 23 OR 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30 32. humans.sh. 33. 31 AND 32 34. 22 AND 33
PsycINFO (Ovid SP)	1. (statin$ OR lipophilic OR hydrophilic).mp. 2. (lovastatin OR simvastatin OR cervistatin OR atorvastatin OR rosuvastatin OR pravastatin OR fluvastatin).mp. 3. Hydroxymethylglutaryl‐CoA Reductase Inhibitors/ all subheadings 4. Alzheimer‐disease/ all subheadings 5. exp dementia‐vascular/ all subheadings 6. creutzfeldt‐jakob‐syndrome/ all subheadings 7. kluver‐bucy‐syndrome/ all subheadings 8. lewy‐body‐disease/ all subheadings 9. pick‐disease‐of‐the‐brain/ all subheadings 10. Huntington‐disease/ all subheadings 11. delirium/ all subheading 12. wernicke‐encephalopathy/ all subheadings 13. (dement$ OR Alzheimer$).mp. 14. (Lewy$ AND body$).mp. 15. ((cognit$ OR memor$ OR mental) and (decline$ OR impair$ OR los$ OR deteriorate$)).mp. 16. (chronic AND cerebrovascular).mp. 17. ((organic brain syndrome) OR (organic brain disease)).mp. 18. ((cerebr$ AND deteriorate$) OR (cerebr$ AND insufficien$)).mp. 19. ((pick$ and disease) or (Creutzfeldt or JCD or CJD) or Huntington$ or Binswanger$ or Korsakoff$).mp. 20. 1 OR 2 OR 3 21. 4 OR 5 OR 6 OR 7 OR 8 OR 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 22. 20 AND 21 23. randomized controlled trial.pt. 24. controlled clinical trial.pt. 25. randomized.ab. 26. placebo.ab. 27. drug therapy.fs. 28. randomly.ab. 29. trial.ab. 30. groups.ab. 31. 23 OR 24 OR 25 OR 26 OR 27 OR 28 OR 29 OR 30 32. humans.sh. 33. 31 AND 32 34. 22 AND 33
LILACS	(statin* OR lipophilic OR hydrophilic) AND (alzheimer$ OR dementia)