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. 2024 May 23;16:112. doi: 10.1186/s13098-024-01349-1

Table 3.

The MetS risk across quartiles of atherogenic indices

Male Female
Model 1
OR (95% CI)
P value Model 2
OR (95% CI)
P value Model 1
OR (95% CI)
P value Model 2
OR (95% CI)
P value
AIP
 Q1; < − 0.08 1 (Reference) 1 (Reference 1 (Reference) 1 (Reference
 Q2; − 0.08–0.09 1.83 (1.34–2.50) < 0.001 1.41 (0.99–1.98) 0.051 2.79 (2.39–3.26) < 0.001 2.50 (2.12–2.95) < 0.001
 Q3; 0.09–0.27 5.76 (4.34–7.64) < 0.001 4.78 (3.49–6.56) < 0.001 12.56 (10.6–14.89) < 0.001 11.78 (9.84–14.11) < 0.001
 Q4; > 0.27 15.21 (11.54–20.06) < 0.001 14.63 (10.66–20.07) < 0.001 77.14 (57.48–103.52) < 0.001 77.56 (57.17–105.24) < 0.001
TC/HDL-c
 Q1; < 3.21 1 (Reference) 1 (Reference) 1 (Reference) 1 (Reference)
 Q2; 3.21–3.81 1.36 (1.04–1.74) 0.014 1.26 (0.95–1.67) 0.1 2.03 (1.76–2.34) < 0.001 1.86 (1.60–2.17) < 0.001
 Q3; 3.81–4.49 2.26 (1.79–2.84) < 0.001 1.89 (1.46–2.46) < 0.001 4.64 (3.99–5.40) < 0.001 4.13 (3.52–4.85) < 0.001
 Q4; > 4.49 4.93 (3.95–6.14) < 0.001 4.34 (3.37–5.60) < 0.001 14.27 (11.73–17.37) < 0.001 12.77 (10.39–15.67) < 0.001
LDL-c/HDL-c
 Q1; < 1.69 1 (Reference) 1 (Reference) 1 (Reference) 1 (Reference)
 Q2; 1.69–2.15 1.05 (0.86–1. 29) 0.60 0.99 (0.78–1.25) 0.91 1.31 (1.14–1.51) < 0.001 1.23 (1.06–1.43) 0.006
 Q3; 2.15-.2.64 1.04 (0.85–1.27) 0.65 0.91 (0.72–1.15) 0.43 2.28 (1.97–2.64) < 0.001 2.02 (1.73–2.36) < 0.001
 Q4; > 2.64 1.62 (1.34–1.96) < 0.001 1.33 (1.07–1.65) 0.01 3.89 (3.32–4.57) < 0.001 3.28 (2.75–3.86) < 0.001
Non-HDL-c
 Q1; < 2.92 1 (Reference) 1 (Reference) 1 (Reference) 1 (Reference)
 Q2; 2.92–3.51 1.17 (0.96–1.42) 0.112 0.99 (0.79–1.25) 0.99 1.37 (1.18–1.59) < 0.001 1.28 (1.09–1.50) 0.002
 Q3; 3.51–4.16 1.51 (1.25–1.83) < 0.001 1.18 (0.95–1.47) 0.13 2.10 (1.81–2.43) < 0.001 1.77 (1.51–2.07) < 0.001
 Q4; > 4.16 1.98 (1.64–2.38) < 0.001 1.48 (1.19–1.84) < 0.001 3.51 (3.01–4.09) < 0.001 2.64 (2.24–3.11) < 0.001
TyG
 Q1; < 8.47 1 (Reference) 1 (Reference) 1 (Reference) 1 (Reference)
 Q2; 8.47–8.85 2.99 (2.16–4.14) < 0.001 2.05 (1.45–2.91) < 0.001 2.54 (2.14–3) < 0.001 2.06 (1.73–2.45) < 0.001
 Q3; 8.85–9.30 10.31 (7.59–14.01) < 0.001 7.54 (5.40–10.51) < 0.001 15.40 (12.91–18.36) < 0.001 12.63 (10.54–15.14) < 0.001
 Q4; > 9.30 26.12 (19.23–35.47) < 0.001 20.74 (14.83–29) < 0.001 64.73 (50.31–82.86) < 0.001 52.47 (40.48–68.02) < 0.001

Model 1: crude model. Model 2: adjusted for age, BMI, physical activity, energy intake, and smoking

AIP atherogenic index of plasma, TC total cholesterol, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, TyG index triglyceride-glucose, CI confidence interval, OR odds ratio