Fig. 5.

Flow cytometric analysis of murine cd4, human CD4, murine cd8, H2K^b, and HLA-DR on day −2 (2 days before transplantation) and day 27 (a), and day −2 and 54 (b) after transplantation. A decrease of murine cd4-expressing T-cells, an increase of human CD4-expressing T-cells, and HLA-DR-expressing cells indicates engraftment of transplanted cells in Balb/c^wt recipient mice after allogeneic transplantation of 2 × 10⁷ BM cells and 2 × 10⁷ splenocytes from human CD4⁺ C57Bl/6-TTG mice with (b) or without (a) pre-incubation of MAX.16H5 IgG₁ (four independent experiments for transplantation of cells from human CD4⁺ C57Bl/6-TTG mice into Balb/c^wt mice with or without short-term pre-incubation of MAX.16H5 IgG₁, n = 10 and 28)