Fig. 4.

Different sensibility to oxidative damage of the anterior chamber tissues. Basal damage (blue columns) is greater in cornea than in trabecular meshwork and iris. Cornea is the most exposed tissue to exogenous ROS sources. After treatment with H₂O₂ (red columns) the most relevant increase in oxidative DNA damage is detected in trabecular meshwork (TM), whose natural defences against reactive oxygen species are minimal due to its position repaired from the direct action of ROS exogenous sources (data from Izzotti et al. [76])