Table 4.

Tenascin (keyword: tenascin and osteoblast, 2006–2011 and published in English)

Author	Type	Sample	Objective	Result
Juhasz et al. [187]	In vitro	Cholesteatoma tissue samples	To identify factors that could play important role during the invasion of the disease	TN and MMP-9 can be key molecules of bone destruction during cholesteatoma progression
Mikura et al. [181]	In vivo	Mouse	To investigate the roles of tenascin-W in osteogenesis	Tenascin-W is expressed in osteoblasts at the edge of the developing bone domain prior to mineralization in mouse fetuses. Tenascin-W is involved in osteoblast maturation (i.e., mineralization)
Meloty-Kapella et al. [182]	In vitro	Avian osteoblasts	To examine possible roles for tenascin-W in osteogenesis	Tenascin-W can accelerate the formation of new bone in a complex multicellular environment
Zhang et al. [20]	In vitro	Rat BMSCs	To investigate the effect of uniaxial stretching on the orientation and biological functions of BMSC	Cyclic stretching promotes the synthesis of collagen types I and III and tenascin-C by the rat BMSC
Kimura et al. [183]	In vivo	ATDC5 osteo-chondroprogenitors	To identify a cDNA encoding mouse tenascin-W (TN-W) upregulated by bone morphogenetic protein (Bmp)2	TN-W is a novel marker of preosteoblasts in early stage of osteogenesis, and that TN-W inhibits cell proliferation and differentiation of preosteoblasts mediated by canonical Wnt signaling