Table 2.
List of identified and putative Cdk-binding partners in Dictyostelium discoideum
| Gene | Protein | dictyBase gene ID | Binding partner |
|---|---|---|---|
| cycA | Cyclin A | DDB_G0279085 | Cdk1 (predicted) |
| cycB | Cyclin B | DDB_G0275493 | Cdk1 [36, 40] |
| cycC | Cyclin C | DDB_G0274139 | Cdk8 [87]a |
| cycD | Cyclin D | DDB_G0277439 | Cdk1 (predicted) |
| cycH | Cyclin H | DDB_G0268668 | Cdk7 (predicted) |
| cycK | Cyclin K | DDB_G0286617 | Cdk9 (predicted) |
| cycL | Cyclin L | DDB_G0285553 | Cdk11 (predicted) |
| psaA | Puromycin-sensitive aminopeptidase | DDB_G0270994 | Cdk5 [43] |
| calA | Calmodulin | DDB_G0279407 | Cdk5 [60] |
| cksl | Cyclin-dependent kinases regulatory subunit | DDB_G0271642 | Unknown |
aAlthough a direct interaction between Cdk8 and CycC has not yet been shown, the two proteins are detected in high molecular weight fractions isolated from Dictyostelium nuclei