Fig. 4.

Regulation of gene expression by Sox4. So far, two modes of regulation of gene expression by Sox4 have been identified; transcriptional and post-translational. At the transcriptional level, Sox4 can act both as a transcription factor and repressor, depending on the gene or cell type of interest. This differential regulation of gene expression, which is discussed in the text, plays a very important role in oncogenic or tumor suppressive functions of Sox4. It should be noted that not all of the illustrated complexes are present in every type of cell