Fig. 2.

Meiotic chromosome arrangement and dynamics in S. pombe and C. elegans. a Telomere clustering and chromosome arrangement during meiotic prophase in S. pombe. Telomeres are clustered at the SPB while centromeres are located away from it, resulting in a bouquet-like chromosome arrangement. b Chromosome and nuclear dynamics during meiotic prophase in S. pombe. Microtubules extending from the SPB interact with the cell cortex, and pull the nucleus, causing back-and-forth nuclear movements between the cell ends. Telomere clustering and nuclear movements promote side-by-side alignment of homologous chromosomes from the bundled telomeres and contact of homologous regions. c Dynamics of PCs in C. elegans. PCs move along the nuclear periphery by interacting with cytoplasmic microtubules via the LINC complexes. The PCs repeatedly associate and dissociate, and eventually interact with their homologous partners. Black arrows indicate PC movements. In a and c, blue or red lines indicate respective pairs of homologous chromosomes. NE nuclear envelope