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. 2024 May 7;15:1380304. doi: 10.3389/fphar.2024.1380304

FIGURE 4.

FIGURE 4

Root-mean-square deviation (RMSD) value of the DNA and the heavy atoms of proteins and inhibitors along 100 ns molecular dynamics simulations for the TOP1/EVO-1 (left) and TOP1/EVO-6 systems (right). TOP1, topoisomerase 1.